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Clinical Trials
Trial Name:

NSABP B-37
Intro: NSABP B-37: A Randomized Clinical Trial of Adjuvant Chemotherapy for Radically Resected Loco-Regional Relapse of Breast Cancer.
Condition:
Description: This study will compare two different types of treatment in patients who have been diagnosed with returning breast cancer in an operated-on breast, the surgical scar, the chest wall, or the regional lymph nodes. In addition to evaluating the effectiveness of the two treatments, the study will also look at quality of life. Patients will be placed in either Group A to be given standard therapy (surgery to remove the recurrent cancer) and, if the doctor believes it appropriate, radiation therapy and/or hormonal therapy (which typically last for at least 5 years), or Group B which is identical to Group A, but also includes chemotherapy for approximately 3-6 months. Patients will not be given specific drugs as part of the study and can follow the recommendation of their doctors.
Criteria:
  1. Must have verified first local and/or regional recurrence of invasive breast cancer following primary treatment with mastectomy or breast conserving treatment 
  2. Must have surgical resection of the recurrence with uninvolved (clear) margins or surgical resection with microscopically involved margins (RI) 
  3. Cannot have evidence of distant metastasis on standard staging examinations 
  4. Must have measurement of hormone receptors in the recurrent tumor 
  5. Must be medically suitable for chemotherapy of 3 to 6 months duration
Contact: For Cancer Information, Current Clinical Trials, and Referral to a Physician please call (216) 844-5432 or (800) 641-2422

Participant Confidentiality:

All information regarding participation in Clinical Trials is treated with the utmost confidentiality. University Hospitals Case Medical Center and the Division of Clinical Research recognize and respect the confidentiality of this information. Access to information related to clinical trials and their participants is restricted to authorized clinical trials personnel only.

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