Retina Diseases Image Analysis Reading Center

Retinal Diseases Image Analysis Reading Center (REDIARC) was founded in 1999. The primary function of REDIARC is to evaluate the pathology of fundus photographs, fluorescein angiograms, or other retinal imaging modalities for prospective clinical trials, including evaluation of fundus photographs and fluorescein angiograms, certification of photographers and clinical sites, and analysis of study results. REDIARC is located at Midtown Tech Park in Cleveland, Ohio, near the University Hospitals Cleveland Medical Center campus and the Case Western Reserve University campus, and is comprised of employees that are employed through either the hospital or university.

Efforts of the center are directed through the Principal Investigator, Douglas Rhee MD, in conjunction the Co-PI / Director of Grading, Baseer Ahmad, MD, and with the Director, Beth Ann Benetz, MA, CRA, FOPS. REDIARC is governed by the University Hospitals Institutional Review Board (IRB), which is fully accredited by AAHRPP. Staff follows the regulations set forth by Good Clinical Practices (GCP), International Conference on Harmonization (ICH), Department of Health and Human Services (DHHS), and Food and Drug Administration (FDA) regulations.

REDIARC is an experienced Reading Center that has analyzed images taken at over 26,000 patient visits over the past 15 years. During the course of those studies, REDIARC has granted more than 2,600 study-specific photographer certifications and 1,900 study-specific system certifications in 37 countries around the world and across 43 U.S. states.

  • Age-related macular degeneration (AM) - wet and dry
  • Diabetic retinopathy (DR) and diabetic macular edema (DME)
  • Uveitis (active, inactive, non-infectious, Behçet’s disease)
  • Non-proliferative diabetic retinopathy (NPDR)
  • Retinitis pigmentosa (RP)
  • Retinal vascular changes in Alzheimer's disease
  • Effects of severe altitude on the retina

Safety and efficacy of various devices and therapies

Online Resources

The following online resources are available:

For more information on our services, please email rediarc@case.edu.

Contact Us for More Information

To learn more about the Retinal Diseases Image Analysis Reading Center, contact:

Douglas J. Rhee, M.D.
REDIARC Medical Director

216-844-8590

Beth Ann Benetz, MA, CRA, FOPS
Director, REDIARC

216-844-3615

Nicola Goodall, MSW
CIARC-REDIARC Project Manager

216-844-3197

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