Research & Clinical Trials

University Hospitals Leads Innovative Clinical Research on Spinal Surgery Techniques

Along with Case Western Reserve University School of Medicine, the Comprehensive Spine Center at University Hospitals Neurological Institute conducts breakthrough research focused on improving patient care.

At the Comprehensive Spine Center, current and recent topics of investigation include:

  • Evaluation of the rates of post-operative cerebrospinal fluid leaks in patients treated with DuraSeal Spine Sealant
  • Development of oligodeodrocytes (a type of brain cell) in the spinal cord
  • Functional regeneration and sprouting of respiratory pathways after spinal cord injury
  • Engineering embryonic spinal cord stem cells for spinal cord injury repair
  • HDE Protocol for the diaphragm pacing system for breathing assistance after spinal cord injury
  • Activ-L artificial disc clinical study to evaluate the safety and effectiveness of the Aesculap Activ-LTM artificial disc in the treatment of degenerative disc disease; during artificial disc replacement surgery, a diseased or damaged disc in the spinal column is replaced with a prosthetic replacement

In addition, team members implanted the first cervical artificial disc (ProDisc-C) in Ohio and initiated an FDA Investigational Device Exemption (IDE) trial of a new lumbar artificial disc.

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