Abdominal wall fat pad biopsy procedure involves removing a small portion of the abdominal wall fat pad. The procedure is done most often to test for amyloidosis.

Needle aspiration is the most common method of obtaining an abdominal wall fat pad biopsy. The skin of the abdomen is cleansed, and a local anesthetic may be used to numb the area. A needle is inserted through the skin and into the fat pad under the skin. A small core of the fat pad is removed with the needle and sent to the laboratory for analysis.

No special preparation is usually necessary.

Although your health care provider may have numbed the skin, there can be some mild discomfort or pressure during the needle insertion. Afterward, the area may feel tender or bruised for several days.

This test may be performed when amyloidosis is suspected.

The fat pad tissues are normal.

In the case of amyloidosis, abnormal results will indicate the presence of amyloid, an insoluble protein fiber that impairs organ and tissue function.

The risks are minimal. There is a slight risk of infection. There is also a minor risk of bruising or slight bleeding.