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A Clinical Trial is a research study to answer specific questions about new therapies or new ways of using established treatments. Clinical Trials are used to determine whether new drugs or treatments are both safe and effective. Most current drug therapies were initially developed in past Clinical Trials.
Participants include men, women and children of all ages, races, religions and ethnic backgrounds, depending on the study guidelines. Protection of the rights, safety and welfare of our research participants is always our primary concern. Clinical Trial participants are seen regularly by the research staff to monitor their health and to determine the safety and effectiveness of their treatment. Each Clinical Trial is approved by the Institutional Review Board consisting of healthcare professionals as well as lay people from the community to ensure that risks are monitored and federal regulations are followed.
What follows is a brochure of some of the hundreds of Clinical Trials at University Hospitals of Cleveland that are actively recruiting participants. If you would like to participate, please note that each trial is listed with study-specific contact information. You may also enroll online by selecting the "Enroll in Clinical Trials" link at the left of this screen.
We hope you find this brochure useful, and that you will share it with friends and family who may benefit from one of the studies.
Nathan Levitan, MDChief Medical OfficerUniversity Hospitals of Cleveland
This research study will examine the use of escitalopram (Lexapro) in the treatment of children suffering from depression. ... more
This research study is designed to learn more about preventing atherosclerosis (hardening of the arteries) in children and young adults with Lupus. ... more
A Phase II Study of Concurrent Radiation and Temozolomide Followed by Temozolomide and Lomustine (CCNU) in the Treatment of Children with High Grade Glioma ... more
Chemotherapy for Progressive Low Grade Astrocytoma in Children Less Than 10 Years Old ... more
European Ewing Tumor Working Initiative of National Groups Ewing Tumor Studies 1999 (EURO-E.W.I.N.G. 99) ... more
Intergroup Protocol for Treatment of Children with Hepatoblastoma ... more
A Phase II Study of Sulindac and Tamoxifen in Patients with Desmoid Tumors that are Recurrent or Not Amenable to Standard Therapy ... more
A Randomized Double Blind Placebo Controlled Trial to Assess the Efficacy of Traumeel S for the Prevention and Treatment of Mucositis in Children Undergoing Hematopoietic Stem Cell Transplantation ... more
A Groupwide Biology and Banking Study for Ewing Sarcoma ... more
A COG Soft Tissue Sarcoma Biology and Banking Protocol ... more
A Children’s Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors ... more
A Children’s Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens ... more
A Phase III Randomized, Multicenter Trial Comparing G-CSF Mobilized Peripheral Blood Stem Cell (PBSC) with Marrow Transplantation from HLA Compatible Unrelated Donors ... more
The study is a randomized, parallel group, unblinded, multicenter study that compares two approaches [home-based, portable monitoring (PM) versus attended, laboratory-based polysomnography (PSG) (Lab)] in adults, at least 18 years of age, with a moderate to high probability of obstructive sleep apnea (OSA) and who have been referred to sleep medicine specialists at AASM-accredited sleep centers for evaluation and/or management.