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Patients and Visitors Clinical Trials Listing
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In This Section
For information or to register for screening in a selected trial, call HealthMatch (216) 844-5000

How to enroll

Search the listing of clinical trials below. When you find one which is appropriate for you click more information and you can apply by contacting us directly by phone or by online application form.
Clinical Trials

A Clinical Trial is a research study to answer specific questions about new therapies or new ways of using established treatments. Clinical Trials are used to determine whether new drugs or treatments are both safe and effective. Most current drug therapies were initially developed in past Clinical Trials.

Participants include men, women and children of all ages, races, religions and ethnic backgrounds, depending on the study guidelines. Protection of the rights, safety and welfare of our research participants is always our primary concern. Clinical Trial participants are seen regularly by the research staff to monitor their health and to determine the safety and effectiveness of their treatment. Each Clinical Trial is approved by the Institutional Review Board consisting of healthcare professionals as well as lay people from the community to ensure that risks are monitored and federal regulations are followed.

What follows is a brochure of some of the hundreds of Clinical Trials at University Hospitals of Cleveland that are actively recruiting participants. If you would like to participate, please note that each trial is listed with study-specific contact information. You may also enroll online by selecting the "Enroll in Clinical Trials" link at the left of this screen.

We hope you find this brochure useful, and that you will share it with friends and family who may benefit from one of the studies.

Nathan Levitan, MD
Chief Medical Officer
University Hospitals of Cleveland
Find a Clinical Trial

Trial Name:

ARST 0321
Intro: A Phase II Study of Sulindac and Tamoxifen in Patients with Desmoid Tumors that are Recurrent or Not Amenable to Standard Therapy
Condition:
Description: This study will determine the progression free survival in children with desmoid tumor treated with sulindac and tamoxifen. Tamoxifen and sulindac are given twice daily for up to one year.
Criteria: 1. Must have biopsy proven desmoid tumor at first presentation or any recurrence. Patients with newly diagnosed desmoid tumor are eligible if (a) they have had no prior therapy and (b) they have disease for which complete surgical resection and/or radiation therapy is not feasible. After attempted surgical resection, patients are only eligible if there is gross residual disease than can be measured on MRI scan. Patients with recurrent desmoid tumor are eligible if (a) they have radiographically documented recurrent or progressive disease, (b) prior anti-tumor therapy has not included treatment with non-steroidal anti-inflammatory drugs or estrogen antagonists, and (c) they have had no chemotherapy or radiation therapy for the present recurrence. 2. Must have measurable disease. 3. Patients must have adequate bone marrow, kidney, liver and heart function. 4. Must have a Lansky/Karnofsky performance status of 50-100. 5. Must not have a history of peptic ulcer disease, significant gastrointestinal hemorrhage, deep vein thrombosis, aspirin allergy, diagnosis of hemophilia, von Willebrand’s disease or other clinically significant bleeding diathesis. 6. Must be no greater than 18 years of age.
Contact: For Cancer Information, Current Clinical Trials, and Referral to a Physician please call (216) 844-5432 or (800) 641-2422

Participant Confidentiality:

All information regarding participation in Clinical Trials is treated with the utmost confidentiality. University Hospitals Case Medical Center and the Division of Clinical Research recognize and respect the confidentiality of this information. Access to information related to clinical trials and their participants is restricted to authorized clinical trials personnel only.

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