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Patients and Visitors Clinical Trials Listing
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In This Section
For information or to register for screening in a selected trial, call HealthMatch (216) 844-5000

How to enroll

Search the listing of clinical trials below. When you find one which is appropriate for you click more information and you can apply by contacting us directly by phone or by online application form.
Clinical Trials

A Clinical Trial is a research study to answer specific questions about new therapies or new ways of using established treatments. Clinical Trials are used to determine whether new drugs or treatments are both safe and effective. Most current drug therapies were initially developed in past Clinical Trials.

Participants include men, women and children of all ages, races, religions and ethnic backgrounds, depending on the study guidelines. Protection of the rights, safety and welfare of our research participants is always our primary concern. Clinical Trial participants are seen regularly by the research staff to monitor their health and to determine the safety and effectiveness of their treatment. Each Clinical Trial is approved by the Institutional Review Board consisting of healthcare professionals as well as lay people from the community to ensure that risks are monitored and federal regulations are followed.

What follows is a brochure of some of the hundreds of Clinical Trials at University Hospitals of Cleveland that are actively recruiting participants. If you would like to participate, please note that each trial is listed with study-specific contact information. You may also enroll online by selecting the "Enroll in Clinical Trials" link at the left of this screen.

We hope you find this brochure useful, and that you will share it with friends and family who may benefit from one of the studies.

Nathan Levitan, MD
Chief Medical Officer
University Hospitals of Cleveland
Find a Clinical Trial

Trial Name:

CCG 9952
Intro: Chemotherapy for Progressive Low Grade Astrocytoma in Children Less Than 10 Years Old
Condition:
Description: This study will compare the event-free survival as a result of treatment with either carboplatin and vincristine or a combination of thioguanine, procarbazine, CCNU and vincristine.
Criteria: 1. Progressive disease following surgical excision based on clear radiological or clinical evidence of progression, or an incomplete excision with necessity to begin treatment because of a risk of neurologic impairment with progression. All patients on study must have residual tumor. 2. Astrocytoma or other eligible tumors (oligodendroglial, mixed gliomas, neuronal, chiasmatic-hypothalamic tumor without histologic confirmation) interpreted as low grade (WHO grades I and II). 3. Age less than 10 years. 4. Intrinsic brainstem tumors of the pons or intrinsic to the optic nerve within the orbit without intracranial extension and involvement of the optic chiasm are not eligible. 5. Children with clinically or radiographically progressive tumors must be enrolled and randomized within six weeks of clear radiological or clinical evidence or progression. Children with newly diagnosed incompletely resected tumors who are considered to require immediate therapy must be enrolled within six weeks of surgery. 6. No prior therapy except diuretics, corticosteroids and surgery. 7. Adequate renal function.
Contact: For Cancer Information, Current Clinical Trials, and Referral to a Physician please call (216) 844-5432 or (800) 641-2422

Participant Confidentiality:

All information regarding participation in Clinical Trials is treated with the utmost confidentiality. University Hospitals Case Medical Center and the Division of Clinical Research recognize and respect the confidentiality of this information. Access to information related to clinical trials and their participants is restricted to authorized clinical trials personnel only.

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