The W.O. Frohring Family Resource Center

Part of Rainbow Babies and Children’s Hospital, this center has a resource library with information on parenting, breastfeeding, sibling relationships and much more. Materials may be borrowed for a limited time within the hospital, and copying services are available.

Patients who have recently given birth at MacDonald Women’s Hospital find the library to be an excellent source on topics relating to newborns and their parents. The Frohring Family Resource Center supports a caring and effective partnership between families and their healthcare team by providing general assistance on baby care and health-related issues. You can learn more about the Center on the Rainbow Babies & Children’s Hospital website. Community residents are also welcome to visit or call the center for information.

Health Encyclopedia

Idiopathic autoimmune hemolytic anemia

Antibodies
Antibodies

Definition

  

Idiopathic autoimmune hemolytic anemia is a drop in the number of red blood cells due to a problem with the body's defense (immune) system.


Alternative Names

  
Autoimmune hemolytic anemia; Anemia - idiopathic autoimmune hemolytic

Causes, incidence, and risk factors

  

Idiopathic autoimmune hemolytic anemia is an acquired disease that occurs when antibodies form against a person's own red blood cells. In the idiopathic form of this disease, the cause is unknown.

There are other types of immune hemolytic anemias where the cause may result from an underlying disease or medication. Idiopathic autoimmune hemolytic anemia accounts for one-half of all immune hemolytic anemias. The onset of the disease may be quite rapid and very serious.

Risk factors are not known.


Symptoms

  

Signs and tests

  

Treatment

  

The first therapy tried is usually treatment with prednisone. If prednisone does not improve the condition, a splenectomy (removal of the spleen) may be considered.

Immunosuppressive therapy is given if the person does not respond to prednisone and splenectomy. Imuran and Cytoxan have both been used.

Blood transfusions are given with caution, if indicated for severe anemia, because of the potential that blood may not be compatible and may bring on a reaction.


Support Groups

  


Expectations (prognosis)

  

Adults may have chronic, relapsing disease, but in children the anemia is usually short-lived.


Complications

  
  • Infection (from treatment)
  • Severe anemia

Calling your health care provider

  

Call your health care provider if you notice symptoms of anemia.


Prevention

  

There is no known prevention for idiopathic autoimmune hemolytic anemia, because the cause is unknown.


 
Review Date: 2/6/2007
Reviewd By: William Matsui, MD, Assistant Professor of Oncology, Division of Hematologic Malignancies, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD. Review provided by VeriMed Healthcare Network.
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