Clinical Trials Listing

Trial Name

Barrett's Esophagus

This study is designed to determine whether there is an increased incidence of Barrett's esophagus or esophageal cancer in the relatives of persons with Barrett's esophagus or esophageal cancer.

Bipolar Disorder, Older Adults

This research study compares lithium and valproate (Depakote) in the treatment of older adults with bipolar manic (high mood) and hypomanic episodes (slightly high mood) ... more

Cancer, Ovarian, Fallopian Tube or Peritoneal

This research study is designed study a treatment for ovarian, fallopian tube or peritoneal cancers. ... more

Diabetes and Kidney Disease

This research study is designed to determine whether the study medication will slow the progress of kidney disease in individuals with Type II Diabetes.

Hair Loss

The Skin Study Center of the Department of Dermatology is doing basic research into the cellular causes of hair loss (alopecia).

HIV, Prevention of Fat Loss

The HIV Metabolic Research Center is conducting the HIV Lipoatrophy Study to understand how HIV infected adults can avoid the disfigurement of fat loss.

Myasthenia Gravis

This research study is designed to determine whether thymectomy (surgical removal of the thymus) helps participants with myasthenia gravis (MG) get better compared to using only medications like prednisone that suppress the immune system. ... more

Posttraumatic Stress Disorder (PTSD), Children and Adolescents

This research study is designed for children and adolescents who have experienced a trauma (e.g. sexual/physical abuse, violence, a car accident) and then developed posttraumatic stress disorder (PTSD).

Skin Conditions, Pre-Malignant and Malignant

The Skin Study Center in the Department of Dermatology is conducting a research study for adults with Actinic keratoses (AK), Bowen's disease, Squamous cell carcinoma, Basal cell carcinoma, or Mycosis fungoides (MF stages IA, IIA, IB, or IIB). ... more

Skin Study

The Skin Study Center of the Department of Dermatology is doing basic research into the cellular causes of psoriasis. ... more

Stroke #2

The Neurological Institute Clinical Trials Unit is conducting a research study to find out if treatment with either aspirin alone or aspirin and Plavix® help to prevent another stroke in people who recently suffered a "lacunar stroke&qu

Stroke #3

This research study is designed to compare two treatments for inidividuals who have a Patent Foramen Ovale (PFO; an opening in the heart) and who had a recent stroke. ... more

Stroke and Insulin Resistance

The Department of Neurology is conducting a research study to determine whether pioglitazone, a medication used to treat diabetes, may help prevent another stroke in patients who have been diagnosed with insulin resistance and who have already

Urea Cycle Disorders

The Longitudinal Study of Urea Cycle Disorders (UCDs) will follow individuals with UCDs so that more can be learned about the natural history of all eight forms of the disorder.

A Randomized Controlled Trial of Vitamin D Therapy in Heart Failure Patients

A Randomized trial of Vitamin D and Calcium therapy versus Placebo and Calcium in patients 60 years or older with Heart Failure from any cause. ... more

Generalized Anxiety Disorder & Bipolar Disorder

The Mood Disorders Program of University Hospitals Case Medical Center is conducting clinical research on the treatment of symptoms related to Generalized Anxiety Disorder and Bipolar Disorder with or without Substance Use Disorder. ... more

Major Depressive Disorder & Generalized Anxiety Disorder

The Mood Disorders Program of University Hospitals Case Medical Center is conducting clinical research on the treatment of symptoms related to Major Depressive Disorder with Generalized Anxiety. ... more

Major Depression and Metabolic Syndrome

The Mood Disorders Research Program of University Hospitals Case Medical Center is conducting clinical research on the treatment of symptoms related to Major Depressive Disorder. ... more

Bipolar Disorder and Major Depression Registry

The Mood Disorders Program of University Hospitals Case Medical Center is building a Registry to collect demographic information on a wide cross section of patients with a mood disorder. ... more

Cataracts and Dementia

 University Hospitals Case Medical Center and Case Western Reserve University are now enrolling patients in a research study sponsored by the National Institutes of Health. 

In the study, we will learn more about how cataract removal impacts patients with dementia in their daily activities, quality of life, vision, mood, and performance on tests of memory and thinking.

Healthy Volunteers Database

The Infectious Diseases Clinicals Trial Unit is currently recruiting individuals for a Healthy Volunteers Database.

LEADER Study

This study is designed to further understand the increased risk of heart disease and explore ways to reduce it in people with type 2 diabetes. This clinical study involves a novel treatment that has been demonstrated to improve glycemic control in people with type 2 diabetes.

Immunity againest Mycobacterium Tuberculosis

The purpose of this study is to understand how immune responses within the lung protect against respiratory infection with Mycobacterium tuberculosis, the organism that causes tuberculosis (Tb).  The investigatior are seeking healthy adults who have been had positive skin tests or blood tests for Tb or received the Tb vaccine, called BCG.  Healthy non-smokers will also be recruited as a control group.