• Clinical Instructor, Ophthalmology, CWRU School of Medicine



Dr. Pankaj C. Gupta arrived to the University Hospitals Eye Institute in 2012 and serves as the Director of Cornea and Refractive Surgery of the Department of Ophthalmology and Visual Sciences. He also acts as Residency Program Director. He is a cornea and refractive surgery specialist, uveitis specialist, and board-certified ophthalmologist. Previously, he joined Georgia Regents University as an assistant professor and the Director of the Cornea Service. While in Augusta, he co-founded the Uveitis Service as well as becoming the Director.

Dr. Gupta graduated medical school from the Ohio State University College of Medicine and Public Health while affiliated with the Cleveland Clinic Foundation. After graduation, he finished an internship at the University of Pittsburgh affiliated Mercy Hospital. Dr. Gupta completed his ophthalmology residency at the Cleveland Clinic Foundation, Cole Eye Institute. He completed a two-year clinical cornea and refractive surgery fellowship at Massachusetts Eye and Ear Infirmary, Harvard Medical School with the second year as chief fellow. Subsequently, Dr. Gupta joined the faculty at Georgia Regents University for four years while obtaining a Masters in Clinical and Translational Sciences prior to moving to Cleveland to join University Hospitals Eye Institute.

Clinical Interests

Dr. Gupta cares for both adult and childhood corneal disease with curiosities specifically in complex as well as high-risk cases. Dr. Gupta is interested in herpes zoster ophthalmicus, herpes simplex, anterior uveitis, infectious keratitis, keratoconus, as well as Fuch’s endothelial corneal dystrophy. He also performs novel surgeries including the Boston Keratoprosthesis that he brought to Georgia for both adult and pediatric patients. After joining University Hospitals, he continued to perform Descemet stripping Automated Endothelial Keratoplasty in adult patients while expanding this technology to infants. He is now advancing the field by performing transplantation of only the corneal endothelium (Descemet Membrane Endothelial Keratoplasty) as one of the only centers in Ohio, while being invited to lecture and teach this new technology nationally.

Other Notable Facts

Dr. Gupta previously was a member of the internal advisory board of the Vision Discovery Institute at Georgia Regents University while acting as the Director for the Distinguished Seminar Series inviting notable speakers such as Dr. John Dowling of the National Eye Institute.

While at University Hospitals, Dr. Gupta worked diligently to improve the care and efficiency of the Eye Institute by actively participating in the Operations Committee providing an improved patient experience from water in the waiting room to improved equipment to help with the diagnosis of eye disease. He has, with the help of Dr. Faruk Örge, worked to integrate the new electronic medical record to further the improved patient care, after looking at over a dozen other complex options.

Recently Dr. Gupta was honored to be selected as one of the next young leaders of the Eye Bank Association of America. This was furthered with an invitation among this select group to speak on his education and surgical experience in DMEK. This group then selected him to act as their spokesperson for the next innovations in education in the field of eye banking to improve the opportunity for more donated corneas to be properly placed from surgery, to research, to education.

Dr. Gupta is passionate about education. While in Augusta, he was the faculty advisor to both the Medical Student Ophthalmology Interest Group as well as the Sight Savers Interest Group. In 2010, Dr. Gupta was honored with Outstanding Young Clinical Science Faculty Award. After moving to Cleveland, he continued his avid engagement, becoming the faculty advisor to the Medical Student Ophthalmology Interest Group as well as the faculty advisor for Case for Sight, the Undergraduate Ophthalmology Interest Group. He was appointed Associate Program Director and Local Director for the residency program in 2013 and became Residency Program Director in 2014. Dr. Gupta continues his teaching while being invited to speak locally, regionally, and nationally.

Video Library

Board Certifications

American Board of Ophthalmology - Ophthalmology

Education & Training


1997, Cornell University

Medical / Professional School(s)

2002, The Ohio State University College of Medicine


2003, Transitional Year - UPMC Mercy-Mercy Hospital of Pittsburgh


2006, Ophthalmology - Cleveland Clinic


2008, Cornea Disease and External Refractiv - Massachusetts Eye and Ear Infirmary

Office Locations

UH Case Medical Center
Department of Ophthalmology
11100 Euclid Ave
Cleveland, OH 44106
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UH Landerbrook Health Center
5850 Landerbrook Dr
UH Eye Institute, Ste 306
Mayfield Heights, OH 44124
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Research Interests

While in Augusta, Dr. Gupta maintained active involvement in the Internal Review Board both within the department as well as for the hospital. He continues collaborations with Basic Science faculty to improve the quality of ophthalmology. Currently, he is part of the Cornea Preservation Time Study, the largest national cornea study to date. Dr. Gupta has previously collaborated with Dr. Ram Nagaraj to help understand lens epithelial cells. His current research interests also include clinical case reports, infectious keratitis, corneal endothelial cells, as well as the education of the next leaders in ophthalmology.

Industry Relationships

University Hospitals is committed to transparency in our interactions with industry partners, such as pharmaceutical, biotech, or medical device companies. At UH, we disclose practitioner and their family members’ ownership and intellectual property rights that are or in the process of being commercialized. In addition, we disclose payments to employed practitioners of $5,000 or more from companies with which the practitioners interact as part of their professional activities. These practitioner-industry relationships assist in developing new drugs, devices and therapies and in providing medical education aimed at improving quality of care and enhancing clinical outcomes. At the same time, UH understands that these relationships may create a conflict of interest. In providing this information, UH desires to assist patients in talking with their practitioners about industry relationships and how those relationships may impact their medical care.

UH practitioners seek advance approval for certain new industry relationships. In addition, practitioners report their industry relationships and activities, as well as those of their immediate family members, to the UH Office of Outside Interests annually. We review these reports and implement management plans, as appropriate, to address conflicts of interest that may arise in connection with medical research, clinical care and purchasing decisions.

View UH’s policy (PDF) on practitioner-industry relationships.

For calendar year 2013, Pankaj Gupta, MD did not disclose any Outside Relationships with Industry.