Loading Results
We have updated our Online Services Terms of Use and Privacy Policy. See our Cookies Notice for information concerning our use of cookies and similar technologies. By using this website or clicking “I ACCEPT”, you consent to our Online Services Terms of Use.

Thrombosis Panel

The Thrombosis Panel includes testing for Prothrombin (Factor II) G20210A mutation analysis and Factor V Leiden mutation analysis with reflex to Factor V HR2 if the Factor V Leiden testing is positive. Individuals with multiple thrombophilic mutations develop venous thromboembolism at a younger age and are at higher risk for recurrent thrombosis than those with a single defect.

The panel may be ordered as is or the tests may be ordered individually.

Indications for Testing

  • Deep vein thrombosis
  • Pulmonary embolism
  • Stroke
  • Superficial venous thrombosis, phlebitis or thrombophlebitis
  • History of thromboembolism
  • Premature cardiovascular disease
  • Peripheral vascular artery disease
  • Acute myocardial infarction
  • Personal history of 2 or more blood-clotting incidents
  • Family history of blood clots, early stroke or premature vascular artery disease
  • Unexplained early-onset severe preeclampsia, placental abruption, or significant intrauterine growth retardation
  • Recurrent unexplained first-trimester losses

Sample Handling

3 – 4 mL whole blood in purple top (EDTA) tube

Sample Handling

Blood samples should be refrigerated or kept cold. Blood samples should never be frozen.Specimens being sent from outside facilities should be packaged according to standard medical safety practices with a cold pack. The specimen should be shipped by overnight priority [scheduled to arrive by Friday AM at the latest].

Shipping Address

Center for Human Genetics Laboratory
10524 Euclid Avenue, Sixth Floor
Cleveland, OH 44106
216-983-1134

For local samples, please call Client Service (216-844-5227) to arrange for sample pick-up.

Turnaround Time

Three to nine days

CPT Codes

Factor V Leiden 81241
Prothrombin 81240

Please submit a completed Molecular Requisition for each sample.