Valdir C. Colussi PhD, Clinical Chief of Medical Physics
Specialty: Photodynamic Therapy, External Beam Radiotherapy, Brachytherapy, Special procedures (TBI, TSEI, Intra-Operative Radiation Therapy, and Gamma-Knife))

Primary Office Location Information (address and phone):
Lerner Tower B181, UH-Case Medical Center
11100 Euclid Avenue
Cleveland, OH 44106
216-844-2531

Education and Certifications:

• Postdoctoral Fellowship: Case Western Reserve University - 1998
• PhD, Medical Sciences: University of Campinas - 1997
• MS, Atomic and Molecular Physics : University of São Paulo – 1992
• BS, Theoretical and Experimental Physics: University of São Paulo - 1990
• ABR Board Certified -2005

Publications:

• EH Zhou, RJ Ellis, E Cherullo, V Colussi, F Xu, W-D Chen, S Gupta, CC Whalen, D Bodner, MI Resnick, AA Rimm, and SM Koroukian. Radiotherapy and Survival in Prostate Cancer Patients: A population-based study. Int. J. Radiation Oncology Biol. Phys. 2008 Jun 4. [Epub ahead of print].
• Miller J, Baron E, Scull H, Hsia A, Berlin J, McCormic T, Colussi V, et al. Photodynamic therapy with the phthalocyanine photosensitizer Pc4 : The case experience with preclinical mechanistic and early clinical-translational studies. Toxicol Appl Pharmacol. 2007; 224: 290-299
• Ellis R, Zhou H, Kaminsky D, Fu P, Kim E, Sodee D, Colussi V, et al. Rectal morbility after permanent prostate brachytherapy with dose escalation to biologic target volumes identified by SPECT/CT Fusion. Brachytherapy. 2007; 6: 149-156.
• Ellis R, Zhou H, Kim E, Fu P, Kaminsky D, Sodee D, Colussi V, et al. Biochemical disease-free survival rates following definitive low-dose-rate prostate brachytherapy with dose escalation to biologic target volumes identified with SPECT/CT capromab pendetide. Brachytherapy. 2007; 6: 16-25.
• Kunos C, Colussi V, Getty P, Kinsella T. Intraoperative electron radiotherapy for extremity sarcomas does not increase acute or late morbidity. Clin Orthop Relat Res. 2006 May;446:247-52.
• Korytko T, Radivoyevitch T, Colussi V, Wessels BW, Pillai K, Maciunas RJ, Einstein DB. 12 Gy gamma knife radiosurgical volume is a predictor for radiation necrosis in non-AVM intracranial tumors. Int J Radiat Oncol Biol Phys. 2006 Feb 1;64(2):419-24.
• Seo Y, Yan T, Schupp JE, Colussi V, Taylor KL, Kinsella TJ. Differential radiosensitization in DNA mismatch repair-proficient and -deficient human colon cancer xenografts with 5-iodo-2-pyrimidinone-2'-deoxyribose. Clin Cancer Res. 2004 Nov 15;10(22):7520-8. PMID
• Ellis RJ, Vertocnik A, Kim E, Zhou H, Young B, Sodee B, Fu P, Beddar S, Colussi V, Spirnak JP, Dinchman KH, Resnick M, Kinsella TJ. Four-year biochemical outcome after radioimmunoguided transperineal brachytherapy for patients with prostate adenocarcinoma. Int J Radiat Oncol Biol Phys. 2003 Oct 1;57(2):362-70.
• Ellis RJ, Vertocnik A, Sodee B, Zhou H, Kim E, Young B, Fu P, Colussi V, Spirnak JP, Dinchman KH, Resnick MI. Combination conformal radiotherapy and radioimmunoguided transperineal 103Pd implantation for patients with intermediate and unfavorable risk prostate adenocarcinoma. Brachytherapy. 2003;2(4):215-22.
• VC Colussi, AS Beddar, TJ Kinsella, and CH Sibata . In vivo dosimetry using a single diode for megavoltage photon beam radiotherapy: Implementation and response characterization . Journal of Applied Clinical Medical Physics. Fall 2001. 2(4):210-218.
• Abraham D, Colussi V, Shina D, Kinsella T, Sibata C. TBI treatment planning using the ADAC pinnacle treatment planning system. Med Dosim. 2000 winter; 25(4):219-24.
• CH Sibata, VC Colussi, NL Oleinick, TJ Kinsella: Photodynamic Therapy: A new concept in medical treatment (Review). Brazilian Journal of Medicine and Biological Research. 2000; 33(8):869-880 .

Albin Gonzalez Ph.D. DABR RSO, Chief Medical Physicist at Firelands Regional Medical Center
Specialty: Radiation Therapy Physics

Primary Office Location Information (address and phone):
Firelands Cancer Center
701 Tyler Street
Sandusky, OH 44870
(419) 557-7480
Email: physicist@firelands.com

Education and Certifications:

• PhD, Physics: Vanderbilt University - 2002
• MS , Physics: Vanderbilt University – 1999
• BS, Physics: University of Panama - 1996
• ABR Board Certified: Therapeutic Radiological Physics – 2005
• Radiation Expert (State of Ohio)

Publications:

• Gonzalez A, Bauer L, Kinney V, and Crooks C. Clinical Implementation of Megavoltage Cone Beam CT As Part Of An IGRT Program. AIP Conf. Proc. 991, 127 (2008)
• Li HH, Gonzalez A, Ji H, and Duggan D. Dose response of BaFBrI:Eu 2+ storage phosphor plates exposed to megavoltage photon beams. Med. Phys. 34, 103 (2007)
• Gonzalez A, Li H, Mitch M, Tolk N, Duggan D. Energy response of an imaging plate exposed to standard beta sources. Appl Radiat Isotopes. (2002); 57: 875-882.
• Hallahan D, Geng L, Cmelak A, Chakrararthy A, Martin W, Scarfone C, Gonzalez AL. Targeting drug delivery to radiation-induced neoantigens in tumor microvasculature. J Control Release. (2001); 74: 183-191.
• Duggan D, Gonzalez A, Coffey II C and Janicki C.Dose model for a beta-emitting stent in a realistic artery consisting of soft tissue and plaque. Med Phys. Volume 26, Issue 11, pp. 2451-2460 (1999).
  
  

Ravi Kulasekere Ph.D., Assistant Professor, Medical Physicist
Specialty: Tomotherapy, IGRT, Film Dosimetry, In Vivo Dosimetry, Special Procedures in Medical Physics

Primary Office Location Information (address and phone):
Lerner Tower B181
UH-Case Medical Center
11100 Euclid Avenue
Cleveland, OH 44106
216-844-2518

Education and Certifications:

• PhD, Neutron Reflectometry from Thin Films: University of Missouri-Rolla
• Post Doctoral Training: University of Michigan-Ann Arbor
• ABR Board Certified: Therapeutic Radiological Physics - 2008

Publications:

• Kunos C, Dobbins D, Kulasekere R, Latimer B, Kinsella T. Comparison of helical tomotherapy versus conventional radiation to deliver craniospinal radiation. Technol Cancer Res T. 2008; 7: 155-268.
• Keiler L, Dobbins D, Kulasekere R, Einstein D. Tomotherapy for prostate adenocarcinoma: A report on acutre toxicity. Radiother Oncol. 2007; 84: 171-176.
• Kulasekere R, Moran JM, Fraass BA, Roberson PL. Accuracy of rapid radiographic film calibration for intensity-modulated radiation therapy verification. J Appl Clin Med Phys. 2006 May 25;7(2):86-95.
  
  

Chunhui (Charlie) Luo Ph.D., Assistant Professor and Medical Physicist
Specialty: IMRT, IGRT, Treatment Planning, Quality Assurance , Radiosurgery

Primary Office Location Information (address and phone):
Lerner Tower B181, UH-Case Medical Center
11100 Euclid Ave
Cleveland, OH 44106
216-844-2 702

Education and Certifications:

• Residency Training: Radiation Oncology Physics,
• University of California Davis Medical Center -- 2005
• PhD, Experimental High Energy Physics: Indiana University – 2003
• MS, Experimental High Energy Physics:
• Institute of High Energy Physics, Chinese Academy of Science- 1997
• BS: University of Science and Technology of China - 1992
• ABR Board Certified: Therapeutic Radiological Physics - 2008

Publications:

• Luo C, Yang CC, Narayan S, Stern RL, Perks J, Goldberg Z, Ryu J, Purdy JA, Vijayakumar S. Use of benchmark dose-volume histograms for selection of the optimal technique between three-dimensional conformal radiation therapy and intensity-modulated radiation therapy in prostate cancer. Int J Radiat Oncol Biol Phys. 2006 Nov 15;66(4):1253-62.

Marcel Marcu M.S., Medical Physicist
Specialty: IMRT, Brachytherapy

Primary Office Location Information (address and phone):
Southwest General Health Center
18697 Bagley Road
Middleburg Heights, OH44130
440-816-6048

Education and Certifications:

• MS: McMaster University, Canada -1996
• MS: University of Bucharest, Romania - 1981
• ABR, AAPM Board Certified

Publications:

• Marcu SM, Wu QJ, Pillai K, Weinhous MS. GammaPlan-Leksell Gamma Knife radiosurgery treatment planning verification method. Med Phys. 2000 Sep;27(9):2146-9.

Kujan Pillai MS
Specialty: Total Body Irradiation, Special Procedures

Primary Office Location Information (address and phone):
UH-Chagrin Highlands Health Center
3909 Orange Place
Orange Village, OH 44122
(216) 896-1800

Education and Certifications:

• MS: Sauger University, India
• ABR Board Certified

Publications:

• Marcu SM, Wu QJ, Pillai K, Weinhous MS. GammaPlan-Leksell Gamma Knife radiosurgery treatment planning verification method. Med Phys. 2000 Sep;27(9):2146-9. PMID
• Korytko T, Radivoyevitch T, Colussi V, Wessels BW, Pillai K, Maciunas RJ, Einstein DB. 12 Gy gamma knife radiosurgical volume is a predictor for radiation necrosis in non-AVM intracranial tumors. Int J Radiat Oncol Biol Phys. 2006 Feb 1;64(2):419-24.
  
  

Carl Shields Ph.D., Medical Physicist
Specialty: Radiation Therapy Physics

Primary Office Location Information (address and phone):
Lerner Tower B181, UH-Case Medical Center
11100 Euclid Avenue
Cleveland, OH 44106
216-844-2518

Education and Certifications:

• PhD, Polymer Physical Chemistry: Case Western Reserve University - 1990
• MS , Polymer Physical Chemistry: Case Western Reserve University – 1984
• BS , Chemistry: Wright State University - 1979

D. Randall Smith M.S., Medical Physicist, Research Associate
Specialty: Gamma Knife, IMRT, Tomotherapy, Wellhofer Scanning, LINAC Acceptance and Commissioning, IMRT QA, Film Dosimetry, In Vivo Dosimetry

Primary Office Location Information (address and phone):
Lerner Tower B181, UH-Case Medical Center
11100 Euclid Avenue
Cleveland, OH 44106
216-844-2518

Education and Certifications:

• M.S. Physics: Case Western Reserve University – 2007
• B.S. Chemical Engineering: University of Akron - 1993

Jason Sohn Ph.D., Associate Professor, Associate Director Division of Physics and Dosimetry
Specialty: IMRT IGRT

Primary Office Location Information (address and phone):
Lerner Tower B-181, UH-Case Medical Center
11100 Euclid Avenue
Cleveland, OH 44106
216-844-2518

Education and Certifications:

• PhD: Medical College of Ohio
• MS : University of Wisconsin
• ABR Board Certified
• External Links:
• Sohn Laboratory: http://rophys.meds.cwru.edu

Publications:

• Sohn JW, Mansur D, Monroe J, Drzymala R, et al. Automated EPID analysis of breast intrafractional and interfractional positioning error. Korean Med Phys J. 2006; 17: 24-31.
• Chevtsov A, Calvetti D, Sohn JW, Kinsella T. Regularization of inverse planning for intensity-modulated radiotherapy. Med Phys. 2005; 32: 501-414
• Huq M, Sohn JW, Hendee W. Over the foreseeable future, the growth in technical complexity of radiation therapy will continue to drive the demand for more medical physicists. Med Phys. 2004; 31: 2939-2941.
• Sohn JW, Dempsey JF, Suh TS, Low DA. Analysis of various beamlet sizes for IMRT with 6 MV photons. Med Phys. 2003 Sep;30(9):2432-9.
• Low DA, Dempsey JF, Markman J, Mutic S, Klein EE, Sohn JW, Purdy JA. Toward automated quality assurance for intensity- modulated radiation therapy. Int J Radiat Oncol Biol Phys. 2002 Jun 1;53(2):443-52.
• Low DA, Sohn JW, Klein EE, Markman J, Mutic S, Dempsey JF. Characterization of a commercial multileaf collimator used for intensity modulated radiation therapy. Med Phys. 2001 May;28(5):752-6.
• Drzymala RE, Sohn JW, Guo C, Sobotka LG, Purdy JA. Angular measurement of the cobalt-60 emitted radiation spectrum from a radiosurgery irradiator. Med Phys. 2001 Apr;28(4):620-8.
• Klein EE, Low DA, Sohn JW, Purdy JA. Differential dosing of prostate and seminal vesicles using dynamic multileaf collimation. Int J Radiat Oncol Biol Phys. 2000 Dec 1;48(5):1447-56.
• Suh JH, Barnett GH, Sohn JW, Kupelian PA, Cohen BH. Results of linear accelerator-based stereotactic radiosurgery for recurrent and newly diagnosed acoustic neuromas. Int J Cancer. 2000 Jun 20;90(3):145-51.

Joseph Syh Ph.D., Assistant Professor, Medical Physicist
Specialty: Sterotactic Radiosurgery, HDR, Tomotherapy, IMRT/IGRT

Primary Office Location Information (address and phone):
Lake/University Ireland Cancer Center
9485 Mentor Avenue
Mentor, OH 44060
216-844-2518

Education and Certifications:

• ABR Board Certified
• PhD: University of North Carolina - 1989
• MS : University of Oklahoma - 1986

Publications:

• Zheng Y, Syh J, Greskovich J, Kunos C, Wessels B. A machine independent threshold method for PET target delineation. Med Phys. 2007; 34: 2351.
• Wessels BW, Syh JH, Meredith RF. Overview of dosimetry for Systemic Targeted Radionuclide Therapy (STaRT). Int J Radiat Oncol Biol Phys. 2006;66(2 Suppl):S39-45.

Barry Wessels Ph.D., Professor and Director of Physics and Dosimetry
Specialty: Radiolabeled Antibody Therapy (Dosimetry and Clinical Trials), IGRT, IMRT

Primary Office Location Information (address and phone):
Lerner Tower B181, UH-Case Medical Center
11100 Euclid Avenue
Cleveland, OH 44106
216-844-2518

Education and Certifications:

• Post Doctoral Training: University of Wisconson, Medical Physics - 1976
• PhD, Low-Energy Nuclear Physics: University of Notre Dame – 1975
• BS, Physics: Rensselaer Polytechnic Institute - 1969
• ABR Board Certified: Therapeutic Radiological Physics – 1981
• Radiation Expert (State of Ohio) – 2002 - Present

Publications:

• Wessels BW, The Effect of Model Assumptions on Kidney Dosimetry and Response: Implications for Radionuclide Therapy. J Nucl Med, MIRD Pamphlet No.20. 2008; Accepted for publication.
• Meredith R, Wessels BW, Knox S. Risks to Normal Tissues from Radionuclide Therapy. Seminars in Nuc Med, Book Chapter. 2008; Accepted for publication.
• Kunos CA, Dobbins D, Kulasekere R, Syh JH, Wessels BW, Latimer B, Einstein DB, Kinsella T. Risk of Radiation-induced Vertebral Growth Plate Arrest after Helical TomoTherapy or Conventional Radiation. Amer J of Clinical Oncology. 2008; Accepted for publication.
• Wessels B, Syh J, Meredith R. Overview of dosimetry for systemic targeted radionuclide therapy (STaRT). Int J Rad Onc Phys. 2006; 66: 539-545.
• Street H, Goris M, Fisher G, Wessels B, Cho C, et al. Phase I study of 131I-chimeric (ch) TNT-1/B monoclonal antibody for the treatment of advanced colon cancer. Cancer Biother Radiopharm. 2006; 21: 243-256.
• Korytko K, Radivoyevitch T, Colussi V, Wessels B, et al. 12 Gy gamma knife radiosurgical volume is a predictor for radiation necrosis in non-avm intracranial tumors. Int J Radiat Oncol Biol Phys. 2006; 64: 419-424.
• Siegel JA, Sparks RB, Sharkey RM, Wessels BW, Bolch WE, Bouchet LG, Breitz HB, Meredith RF, Sgouros G, Stabin MG. Blood-based red marrow dosimetry: where's the beef? J Nucl Med. 2005 Aug;46(8):1404-6; author reply 1405-6.
• Patel SJ, Shapiro WR, Laske DW, Jensen RL, Asher AL, Wessels BW, Carpenter SP, Shan JS. Safety and feasibility of convection-enhanced delivery of Cotara for the treatment of malignant glioma: initial experience in 51 patients. Neurosurgery. 2005 Jun;56(6):1243-52; discussion 1252-3.
• Xing L, Wessels BW, Hendee WR. The value of PET/CT is being over-sold as a clinical tool in radiation oncology. Med Phys. 2005 Jan; 32(6): 1457-1458.
• Wessels BW, Bolch WE, Bouchet LG, Breitz HB, Denardo GL, Meredith RF, Stabin MG, Sgouros G; American Association of Physicists in Medicine. Bone marrow dosimetry using blood-based models for radiolabeled antibody therapy: a multiinstitutional comparison. J Nucl Med. 2004 Oct;45(10):1725-33.
• Wu QJ, Chankong V, Jitprapaikulsarn S, Wessels BW, Einstein DB, Mathayomchan B, Kinsella TJ. Real-time inverse planning for Gamma Knife radiosurgery. Med Phys. 2003 Nov;30(11):2988-95.
• Wu QR, Wessels BW, Einstein DB, Maciunas RJ, Kim EY, Kinsella TJ. Quality of coverage: conformity measures for stereotactic radiosurgery. J Appl ClinMed Phys. 2003 Autumn;4(4):374-81.
• Bouchet LG, Bolch WE, Blanco HP, Wessels BW, Siegel JA, Rajon DA, Clairand I, Sgouros G. MIRD Pamphlet No 19: absorbed fractions and radionuclide S values for six age-dependent multiregion models of the kidney. J Nucl Med . 2003 Jul;44(7):1113-47.
• DeNardo GL, DeNardo SJ, Wessels BW, Kukis DL, Miyao N, Yuan A. 131I-Lym-1 in mice implanted with human Burkitt's lymphoma (Raji) tumors: loss of tumor specificity due to radiolysis. Cancer Biother Radiopharm. 2000 Dec;15(6):547-60.
• Wessels BW, Meares CF. Physical and chemical properties of radionuclide therapy. Semin Radiat Oncol. 2000 Apr;10(2):115-22. Review.

Chuck Wissuchek M.S., Medical Physicist
Specialty: Radiation Therapy Physics

Primary Office Location Information (address and phone):
Mercy Medical Center
1320 Mercy Dr. N.W.
Canton, OH 44708
330-489-1000

Education and Certifications:

• MS, Medical Physics: University of Texas at Houston Graduate School of Biomedical Science- 1978
• BS, Physics: Indiana Institute of Technology - 1971
• ABR Board Certified: Therapeutic Radiological Physics- 1987
• Diagnostic Radiological and Medical Nuclear Physics – 1990
• Radiation Oncology Physics – 1990