The IRB review responsibilities of Case Comprehensive Cancer Center Institutional Review Board (Cancer IRB) were transitioned to the IRB offices and committees of the University Hospitals Case Medical Center (UHCMC) on December 12, 2011 and to the Cleveland Clinic (CC) beginning on October 24, 2011. Approvals by the Cancer IRB will remain in effect until further review is undertaken by the UHCMC or CC IRB. All new cancer and cancer-related protocols will be submitted to the IRB of the lead Principal Investigator’s institution using their existing electronic systems (iMedRIS at UHCMC and WebKit at CC). The same procedures apply to amendments, continuing reviews, SAEs, deviations and other protocol-related actions on currently active protocols that were processed and approved previously by the Cancer IRB. These activities will be reviewed by the IRB of the lead Principal Investigator’s institution which will be the IRB of record.
It remains a high priority of the Case CCC to foster clinical research collaborations between the UHCMC and CC. To that end, the IRBs of each hospital have agreed to accept the approval of the other site in a facilitated review arrangement. Thus, opening of clinical trials at both sites requires only a single full board review at the site of the lead investigator.
All cancer and cancer-related research protocols will continue to be submitted to the Case Comprehensive Cancer Center Protocol Review and Monitoring Committee (Case CCC PRMC) for scientific review and approval, prior to review and approval by the respective institutional IRB.
Case CCC PRMC
David Goldblatt
Protocol Review & Monitoring Committee Manager
Tel: (216) 844-5060; Fax: (216) 201-4043; E-mail: david.goldblatt@case.edu
UHCMC Cancer IRB
Website
Cheryl Gipson
Human Subject Protections Specialist
Tel: (216) 844-7829; Fax (216) 844-1547
E-mail: Cheryl.Gipson@UHhospitals.org
Carol Fedor, RN, ND, CCRC
Clinical Research Manager
Tel: (216) 844-5524; Fax (216) 844-1547
E-mail: Carol.Fedor@UHhospitals.org
SCC Clinical Trials Unit
Emily Collins, MA, CCRP
Regulatory Manager, Seidman Cancer Center
Tel: (216)-844-5404; Fax: (216) 844-1061
Email: Emily.Collins@case.edu
Case CCC Clinical Research Office (Case CCC CRO)
Katarzyna Karelus
Case CCC CRO Administrative Director
Tel. 216-844-4176; Fax: 216-844-7832; E-mail: kxk384@case.edu
Cleveland Clinic IRB
Daniel Beyer, MS, MHA, CIP
Ruth Fritskey, RN, MSN, AOCN
Tel. 216-444-2924; E-mail: irb@ccf.org
Taussig Cancer Center
Becky Habecker, BS, CCRP
Research Supervisor
Tel. 216-445-2612; E-mail: habeckb@ccf.org