Research & Clinical Trials: Vascular Medical Advancements Within Reach
UH vascular physicians are committed to investigating new surgical techniques, medications and therapies to treat patients with vascular conditions. Their ongoing involvement in research projects and clinical trials opens doors to new advances that ensure patients receive the best care and support possible.
Research projects and clinical trials currently under way include:
Atrium iCAST Iliac Stent Pivotal Study – UH vascular doctors are investigating the safety and effectiveness of a specific type of stent – the Atrium iCAST iliac stent – in the treatment of iliac occlusive disease. Iliac occlusive disease involves narrowing of the iliac arteries, which branch off from the aorta at hip level to supply the legs with blood.
CORAL (Cardiovascular Outcomes in Renal Atherosclerotic Lesions) – This study involves individuals with a history of systolic hypertension and documented renal artery stenosis (narrowing of one or both of the arteries supplying the kidneys with blood). Physcians are treating patients in this trial by medical therapy alone or medical therapy combined with stenting. Careful monitoring of the patients will help doctors determine whether the combined treatment is more effective in reducing the incidence of adverse cardiovascular and renal events.
CVRX®Rheos® Pivotal Trial – This clinical trial was developed to measure the effectiveness and safety of an implantable medical device designed to control hypertension in individuals whose condition has been resistant to medication. This trial is pivotal to evaluating the risks and benefits of this device prior to its application for FDA approval.
Research is also being conducted for the following conditions:
Infectious diseases and dermatology – Utilizing the tools, technology and expertise of the vascular laboratory, the vascular medicine team provides support services for endothelial function testing to several trials in infectious diseases and dermatology.
Peripheral Artery Disease (PAD) – Our vascular medicine specialists are involved in stem cell research for lower extremity atherosclerosis (PAD) in conjunction with cardiac stem cell research.