The physicians in the Center for Memory and Cognition have produced a voluminous amount of publications in the form of articles in prestigious peer-reviewed journals and book chapters, as well as major books in the field, for example, Diagnostic Criteria in Neurology and the Little Black Book of Neurology: A Manual for Neurologic House Officers.
Members of the Center’s team also are committed to studying and developing promising therapeutics in the field of memory and cognition.
A few or our current projects are:
- Research drug studies in Alzheimer’s disease, Pseudobulbar palsy, Trisomy 21 and aging.
- Assessment of caregiving methods
- Studies of depression in caregivers of Alzheimer’s disease patients
- Multiple studies of the genetics of Alzheimer’s disease
Current Clinical Trials
A Phase 2 Study Evaluating The Efficacy And Safety Of PF 04494700 In Mild To Moderate Alzheimer's Disease
The purpose of this study is to evaluate the efficacy and safety of PF 04494700 in participants with mild to moderate Alzheimer's disease.
Memantine (10mg BID) for the Frontal and Temporal Subtypes of Frontotemporal Dementia
The primary objective of the study is to determine whether memantine is effective in slowing the rate of behavioral decline in frontotemporal dementia.
A Phase 3 Study Evaluating Safety and Effectiveness of Immune Globulin Intravenous (IGIV 10%) for the Treatment of Mild to Moderate Alzheimer´s Disease
The purpose of this study is to determine whether IGIV, 10% treatment, administered at two different doses for 9 and 18 months, results in a significantly slower rate of decline of dementia symptoms in subjects with mild to moderate Alzheimer´s Disease (AD). Subjects will be randomly assigned to receive intravenous infusions of either of two doses of IGIV, 10% or placebo every two weeks for 70 weeks (36 infusions) as an add-on to conventional Food and Drug Administration (FDA)-approved AD medications.